Inflated Estimates of Proportional Recovery From Stroke

The proportional recovery rule for stroke revisited.

Most motor recovery occurs in the first 3 months after stroke. This is often referred to as spontaneous biological recovery (SBR), a process that has been both underinvestigated in humans and underexploited with respect to neurorehabilitation. Data from animal models suggest that SBR is attributable to a unique timelimited period of enhanced postischemic plasticity. In 2008, we defined recovery...

Functional Recovery From Stroke

Background and Purpose Shorter lengths of hospital stay in stroke units could be due to quicker functional recovery or mechanisms of expediting hospital discharge. Methods Stroke survivors with an intermediate prognosis at 2 weeks after stroke (n=146) were randomized for management in a stroke rehabilitation unit or in general wards. Barthel scores were monitored at weekly intervals until hospi...

Memantine enhances recovery from stroke.

BACKGROUND AND PURPOSE Stroke treatment is constrained by limited treatment windows and the clinical inefficacy of agents that showed preclinical promise. Yet animal and clinical data suggest considerable poststroke plasticity, which could allow treatment with recovery-modulating agents. Memantine is a well-tolerated N-methyl-D-aspartate glutamate receptor antagonist in common use for Alzheimer...

Generalisability of the proportional recovery model for the upper extremity after an ischaemic stroke

Generalisability of the maximum proportional recovery rule to visuospatial neglect early post stroke